Searchable abstracts of presentations at key conferences in endocrinology

ea0059p003 | Adrenal and steroids | SFEBES2018

Mass spectrometry-based assessment of childhood androgen excess in 487 consecutive patients

Mannion Pascoe , Elhassan Yasir , Smith Karen , Webster Rachel , Saraff Vrinda , Barrett Timothy , Shaw Nick , Krone Nils , Dias Renuka , Kershaw Melanie , Kirk Jeremy , Hogler Wolfgang , Krone Ruth , O'Reilly Michael , Arlt Wiebke , Idkowiak Jan

Background: Androgen excess in childhood is a common clinical presentation with potentially serious underlying pathology.Objectives and Design: We have examined the diagnostic utility of simultaneous measurement of serum dehydroepiandrosterone sulfate (DHEAS), androstenedione (A4), and testosterone (T) to delineate the biochemical signatures of conditions underlying paediatric hyperandrogenism in a large tertiary care referral centre (2013–2017). Se...